Launching of the 2017 campaign
This Chair allows a researcher from a foreign country to be hosted in one of the laboratories of the IBPC for a period of 3 to 12 months
Thesis Price & Chairs
The Edmond de Rothschild Chair
Edmond de Rothschild Research Chair
In keeping with the spirit of its founder, the Edmond de Rothschild Foundation for scientific Research and Development (FEDR), part of the international network of Edmond de Rothschild foundations, has established an Edmond de Rothschild Research Chair, awarded every two years to attract reknowned foreign researchers in the following areas: bioenergetics, membrane biology, structural biology, microbiology or molecular modelling. The laureate will be hosted in one of the five laboratories of the Institut de Biologie Physico-Chimique (IBPC, 13 rue Pierre et marie Curie - 75005 PARIS- France).
This mechanism is intended to contribute to the promotion of research and to encourage the exchange and reinforcement of IBPC collaborations, to encourage the sharing of experiences, the transmission and dissemination of knowledge through conferences and seminars, to highlight the engagement of scientific personalities in societal issues.
2019 Award Winner: Dr. Hendrik W. van Veen
On December 11th, 2018 the jury of the Edmond de Rothschild Chair awarded the project presented by Hendrik W. van Veen, Professor at Cambridge University, entitled "Membrane bioenergetics and RND-mediated antibiotic resistance ". Hendrik W. van Veen will be welcomed during the 2019 at UMR 7099, directed by Bruno Miroux.
Hendrik W. van Veen earned his B.Sc. and M.Sc. degrees in Biochemistry and PhD degree in Microbiology cum laude at the University of Wageningen. After post-doctoral work at the Universities of Groningen and Oxford, he obtained a research fellowship from the Royal Netherlands Academy of Arts and Sciences. He is currently Reader in Molecular Pharmacology at Cambridge University, and a teaching fellow at Clare College. His research group aims at the molecular mechanisms of multidrug transporters.
He biochemically and functionally characterized the first-known bacterial homologue of the human multidrug resistance P-glycoprotein and expressed this ABC transporter (LmrA) in mammalian cells for a direct comparison of its pharmacological properties with those of P-glycoprotein. Established a role for ion-coupling in the energetics of LmrA in transport studies using membrane vesicles and proteoliposomes and in electrophysiological studies using giant unilamellar vesicles (port-a-patch) and planar bilayers (tip-dip technique). Demonstrated for the first time that catalytic reactions in LmrA can mediate ATP synthesis in the presence of reverse substrate gradients. Determined drug-protein stoichiometries using equilibrium drug binding and transport assays. Established the transport of small molecule drugs by the lipid-A ABC transporter MsbA and a role for proton coupling in the activity of this transporter. Identified structural elements in the human breast cancer resistance protein (ABCG2) that are responsible for protein-drug interactions in the substrate binding pocket. Identified the presence of multiple drug interaction sites in a MFS multidrug transporter (LmrP) and demonstrated variable (substrate-dependent) proton coupling. Discovered that ion coupling in certain bacterial MATE transporters is based on the simultaneous input of the proton-motive force and sodium-motive force. Generated mechanistic interpretations of crystal structures and cryo-EM structures of multidrug transporters in ABC and RND families.
2017 Award Winner: Dr. Arthur GROSSMAN
On June 20th, 2017 the jury of the first edition of the Edmond de Rothschild Chair awarded the project presented by Arthur Grossman, Professor (Carnegie Foundation at Stanford University, California), entitled "Photosynthetic Investigation, Functioning and Biogenesis in a oxic environment ".
Founded in 2017 at the initiative of the Edmond de Rothschild Foundations, the "Edmond de Rothschild Chair" aims to enable internationally renowned researchers from abroad to work for a few months in the laboratories of the Institute of Physico-Chemical Biology ( IBPC). The main mission of the Chair is to support and disseminate research conducted at IBPC, particularly in the areas of bioenergetics, membrane biology, structural biology, microbiology and molecular modeling.
Arthur Grossman will be welcomed during the 2017-2018 academic year at UMR7141 (UPMC-CNRS), directed by Francis-André Wollman. In this context, several conferences and seminars will be organized around Professor Grossman's work on the photobiology of micro-organisms.
Objectives of the call for candidates
The goal of this campaign is to increase the visibility of research at the IBPC, to foster exchanges and to reinforce collaborations, to encourage the exchange of ideas, the transmission and diffusion of knowledge through conferences and seminars, and to underscore the implication of our researchers in socially relevant challenges.